![]() ![]() During the first 6 seasons, Burke, O'Malley, and Stevens all depart the series. Richard Webber ( James Pickens Jr.), Chief of Surgery and attending general surgeon, is the former lover of Ellis Grey. During their internship, they are overseen by Miranda Bailey ( Chandra Wilson), a senior resident, who works with attending physicians Derek Shepherd ( Patrick Dempsey), head of neurosurgery and Meredith's love-interest, and Preston Burke ( Isaiah Washington), head of cardiothoracic surgery, who becomes Yang's fiancé. Knight), who each struggle to balance their personal lives with hectic schedules and stressful residency requirements. During her time as an intern, Grey works alongside fellow physicians Cristina Yang ( Sandra Oh), Izzie Stevens ( Katherine Heigl), Alex Karev ( Justin Chambers) and George O'Malley ( T. The series follows the life of Meredith Grey ( Ellen Pompeo), the daughter of the famous general surgeon Ellis Grey ( Kate Burton), starting from her acceptance into the surgical residency program at the fictional Seattle Grace Hospital (later named Seattle Grace Mercy West and finally, Grey Sloan Memorial Hospital). ![]()
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